What is 3hz spike-and-wave?

Spike-and-wave pattern during sleep In continuous spike-and-wave syndrome (CSWS), a rare form of age-related epilepsy, children between the ages of three and seven exhibit continuous spike-and-wave discharges during slow-sleep. This disorder is found in 0.2–0.5% of all child epilepsy cases.

What is spike-and-wave in EEG?

Slow spike and waves: These bilaterally synchronous discharges occur in the symptomatic generalized epilepsies and are the typical EEG feature of children with Lennox–Gastaut syndrome(LGS). The frequency of these discharges is commonly in the range of 1 Hz to 2.5 Hz.

What causes brain wave spikes?

Spikes or sharp waves are terms commonly seen in EEG reports. If these happen only once in a while or at certain times of day, they may not mean anything. If they happen frequently or are found in specific areas of the brain, it could mean there is potentially an area of seizure activity nearby.

What is a spike in neurology?

n. 1. in behavioral neuroscience, a train of electrical signals recorded from an individual neuron in the brain. Spikes are the action potentials or signals generated by neurons to communicate with one another.

What does generalized epilepsy mean?

Generalized epilepsy is a form of epilepsy in which the seizures come from the entire brain at once. There is typically no warning.

What is Spike waveform?

Spike sorting is a class of techniques used in the analysis of electrophysiological data. Spike sorting algorithms use the shape(s) of waveforms collected with one or more electrodes in the brain to distinguish the activity of one or more neurons from background electrical noise.

What is the difference between seizure and epilepsy?

A seizure is a single occurrence, whereas epilepsy is a neurological condition characterized by two or more unprovoked seizures.

What does spike amplitude mean?

Common definition: Voltage indicating height of action potential. Usually calculated as the difference between AP peak and AP threshold voltages. Commonly measured using first AP in train at rheobase current.

Which are characteristics of neural pools?

Characteristics of neuronal pools:

• Consist of thousands of neurons.
• Can contain both inhibitory and excitatory neurons.
• The output of the entire neuronal pool may stimulate or depress activity in other parts of the CNS.

What is the frequency range of a spike and wave?

The spike-and-wave is a bi-synchronous, symmetric discharge of sudden onset and resolution with a frequency of 3.5 Hz to 4 Hz at the onset, slowing to 2.5 Hz to 3 Hz at resolution. The greatest amplitude is at the superior frontal electrodes.

What is the Spike and wave complex in EEG?

The EEG “spike” of the spike-and-wave complex corresponds to the depolarization of the neuronal membrane potential, also called a paroxysmal depolarizing shift (PDS).

What is the continuous pattern of Spike and wave activity?

This continuous pattern during sleep, like other aspects of spike-and-wave activity, are not completely understood either. However, what is hypothesized is that corticothalamic neuronal network that is involved in oscillating sleep patterns may begin to function as a pathologic discharging source.

Is Spike-and-wave activity caused by a giant EPSP?

Therefore, the theory that spike-and-wave activity is caused by a giant EPSP due to the decrease or the absence of IPSPs ( inhibitory postsynaptic potentials) is not accepted as a general mechanism for epileptic activity. Many studies have shown that the inhibitory postsynaptic signaling is actually increased during these epileptic attacks.